AA at the Belgian Cleanroom Workshop in Antwerp

Our President and Secretary General, Thierry Marchal presented the topic: “Using ISO 14644 to Optimize Contamination Control Strategy: limitations of traditional approaches, complementarity of CFD and promises of Clean Room Digital Twin” at the Belgian Cleanroom Workshop held in Antwerp on 21 October.

We often hope that ISO standards will explicitly refer to engineering simulation. The ISO 14644 is a great example: this standard states that “Computational fluid dynamics (CFD) is a suitable tool for varying this factor while predicting the effectiveness of different cleanroom designs.” and it continues “… the amount of air required for a particular cleanroom is not dependent on the volume of the room, but rather on the nature of the activities within the room and the design of the air distribution system …”, an observation easier to demonstrated through simulation.

Other presentations highlighted the importance of good regulations or illustrated that employees movements in clean rooms could further disperse unwanted particles if people move at speeds greater than 0.5 m/s. Thanks to advanced in silico technologies, CFD models involving moving objects and people, we are able to easily assess the actual risk of contamination. In silico technologies can quickly investigate various alternatives before building the cleanroom and guarantee excellent working conditions for drug manufacturing or operating rooms in hospitals.

As usual, collaboration between different technologies and solutions will accelerate affordable medical innovation for patients.